Sertraline Detox, Side Effects, Dependence, Withdrawal, Timeline & Overdose

What Is Sertraline? Sertraline is one of the most popular antidepressants in the United States. Its brand name is Zoloft, a drug that alleviates depression, obsessive-compulsive disorder (OCD), panic and anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder. In addition, doctors sometimes prescribe Sertraline off-label to treat eating disorders and insomnia as well. Sertraline detox treatment […]


What Is Sertraline?

Sertraline is one of the most popular antidepressants in the United States. Its brand name is Zoloft, a drug that alleviates depression, obsessive-compulsive disorder (OCD), panic and anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder. In addition, doctors sometimes prescribe Sertraline off-label to treat eating disorders and insomnia as well. Sertraline detox treatment will be able to help you in case you have developed a sertraline dependency.

This drug is known for making people develop a dependency on it, for this reason when the person tries to stop using it may experience withdrawal effects. According to the scientific piece ‘Orthostatic hypotension induced by sertraline withdrawal, this medicine may also lead to hypertension problems as an effect of withdrawal.

This research showed that “A patient receiving sertraline for depression developed dizziness and orthostatic hypotension on repeated attempts to discontinue the drug. All other organic factors were ruled out. The hypotension was proved to be secondary to sertraline by repeated rechallenges. After a variety of attempted treatments, the agent was discontinued successfully through an extended titration period.”

Sertraline Detox
Sertraline detox treatment will be able to help you in case you have developed a sertraline dependency.

Sertraline is a selective serotonin reuptake inhibitor (SSRI), a medication that stabilizes serotonin in the brain.  Serotonin is a neurotransmitter that regulates and balances emotions, so many low serotonin levels suffer from depression and other mental disorders.  SSRIs work by blocking the brain’s neurons from absorbing serotonin.  As a result, more serotonin is available to facilitate connections between neurons, relieving conditions that arise from a shortage of neurotransmitters. As a result, people with healthy serotonin levels experience better emotions, sleep more efficiently, and enjoy more incredible energy and interest in life.

Sertraline is a prescription drug that exists in the form of a pill, tablet, or liquid.  In most cases, a person who uses the medication properly will take it only once a day. Sertraline is generally safe, and research has proven that it can be an effective source of treatment.  However, Sertraline also carries risks for misuse, dependence, withdrawal, and overdose.

Sertraline Side Effects

Sertraline oral tablets may cause drowsiness, insomnia, or both. It may also cause other Zoloft side effects.

More common side effects

The adult side effects of this drug are slightly different from the side effects for children. Side effects for adults and children can include:

  • Nausea, loss of appetite, diarrhea, and indigestion
  • Change in sleep habits, including increased sleepiness and insomnia
  • Increased sweating
  • Sexual problems, including decreased sex drive and ejaculation failure
  • Tremor or shaking
  • Tiredness and fatigue
  • Agitation

Serious Sertraline side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Severe allergic reactions. Symptoms can include:
    • trouble breathing
    • swelling of your face, tongue, eyes, or mouth
    • rash, itchy welts (hives) or blisters, alone or with fever or joint pain
  • Low sodium levels: Seniors may be at greater risk for this. Symptoms can include:
    • headache
    • weakness or unsteadiness
    • confusion, problems concentrating or thinking, or memory problems
  • Changes in appetite or weight: You should check the weight and height of children and adolescents often while they take this drug.
  • Suicide attempts
  • Acting on dangerous impulses
  • Aggressive or violent behavior
  • Thoughts about suicide or dying
  • New or worse depression
  • New or worse anxiety or panic attacks
  • Agitation, restlessness, anger, or irritability
  • Trouble sleeping
  • An increase in activity or talking more than normal
  • Abnormal bleeding
  • Seizures or convulsions
  • Serotonin syndrome: This condition can be life-threatening. Symptoms can include:
    • hallucinations and delusions
    • agitation
    • loss of consciousness
    • seizures
    • coma
    • fast heart rate
    • changes in blood pressure
    • muscle tremor or stiff muscles
    • dizziness
    • shakiness
    • sweating
    • nausea
    • vomiting
    • muscle rigidity
  • Manic episodes. Symptoms can include:greatly increased energy
    • severe trouble sleeping
    • racing thoughts
    • reckless behavior
    • unusually grand ideas
    • excessive happiness or irritability
    • talking more or faster than usual
  • Eye pain
  • Changes in vision, including blurred and double vision
  • Swelling or redness in or around your eyes

Sertraline Dependence 

Since Sertraline is a long-term medication, there is no inherent danger in taking it for months or even years. However, since it’s a mind-altering drug, it can cause dependence. When a person becomes unable to feel normal or get through the day without taking Sertraline, they’ve become dependent on the medication. There is a debate about whether Sertraline is addictive because there is no evidence that people who take Sertraline ever have cravings for it. Nevertheless, people who stop taking Sertraline can experience withdrawal.

To avoid withdrawal, some people may continue to use Zoloft even though they believe they no longer need it. In some cases, they might “doctor shop” for more Zoloft prescriptions or buy the medication illegally, all to keep away withdrawal symptoms. This cycle of withdrawal and relapse is characteristic of an addiction disorder. Fortunately, addiction to this prescription drug can be cured with medically supervised Sertraline detox and therapy at a rehab facility.

Sertraline Detox
Fortunately, addiction to this prescription drug can be cured with medically supervised Sertraline detox and therapy at a rehab facility.

Sertraline Detox & Withdrawal

Sertraline Withdrawal is a form of SSRI Discontinuation Syndrome. This condition will affect about 20% of people who use an SSRI. Since Zoloft has a short half-life (the length of time a drug stays in the bloodstream before it leaves the body), when someone decides to stop taking Sertraline, its effects quickly wear off. 

For this reason, if a person suddenly stops taking this drug without going through Sertraline detox, their serotonin levels will abruptly decline. That’s why health care professionals often wean their clients off the medication by gradually reducing the amount they take until they completely stop, a method sometimes called a “tapering strategy.”

The brain will adjust to post-sertraline serotonin levels, but the body may react adversely to lower amounts of serotonin in the nervous system until it does. The symptoms of SSRI Discontinuation Syndrome (Zoloft Withdrawal) usually last for one to three weeks. The severity of the withdrawal symptoms will vary depending on how long a person has taken Zoloft. In many cases, people will experience rebound depression or anxiety when they stop taking the medication. 

Sertraline Detox
If a person suddenly stops taking this drug without going through Sertraline detox, their serotonin levels will abruptly decline. 

Symptoms Of Sertraline Detox & Withdrawal

  • Lack of Concentration
  • Lightheadedness
  • Nausea and Vomiting
  • Chills
  • Dizziness
  • Fatigue
  • Headaches
  • Irritability
  • Insomnia
  • Suicidal Thoughts
  • Tingling Sensations in the skin
  • Vertigo

Sertraline Detox & Withdrawal Timeline

Sertraline Withdrawal symptoms can vary in severity and duration based on the period of use, dosage, individual physiology, and the length of time taken to taper off. Gradually tapering off Zoloft under a doctor’s supervision during Sertraline detox can reduce or avoid the symptoms altogether. Usually, sertraline’s dose is gradually reduced over around four weeks. A sample taper schedule is reducing the dose by 50 mg every 5–7 days to a final dose of 25–50 mg before the drug is stopped.

Sertraline Detox

A gradual reduction in dosage during Sertraline detox will be most effective for managing and controlling withdrawal symptoms. Reducing the sertraline dosage slowly allows your brain to gradually adjust to lower amounts of medication, finally adapting to no medication at all.

Understanding what to expect in terms of symptoms will also help in managing sertraline Withdrawal. Many symptoms are normal, and knowing what they are will reduce anxiety about those symptoms, making them easier to deal with mentally. Talk therapy and other non-medication treatments should be continued normally to treat the psychological withdrawal symptoms of sertraline.

Exercise may also be helpful. Exercise is widely known to improve both mental and physical wellness. Eating a healthy diet may also help. Avoid foods known to increase jitteriness, like caffeine and sweets, and consume healthy, whole foods. Eating a nutrient-rich, well-balanced diet may help with both physiological and psychological issues associated with withdrawal.

Sertraline Detox
A gradual reduction in dosage during Sertraline detox will be most effective for managing and controlling withdrawal symptoms.

Sertraline Overdose

It is possible to overdose on sertraline. An overdose occurs when someone takes too much of the medication. Although many symptoms of a sertraline overdose are uncomfortable, an overdose is not necessarily a life-threatening emergency. However, in severe cases, an overdose can cause organ damage and may even turn fatal. The milder and more common symptoms of an overdose include:

  • Agitation
  • Dizziness
  • Fever
  • Tiredness
  • Increased Heart Rate
  • Nausea And Vomiting
  • Shaking And Tremors

When someone suffers a severe sertraline overdose, they may faint or experience delirium and hallucinations. The overdose could also damage a person’s heart and pancreas. Furthermore, a Sertraline overdose can become serotonin syndrome. Serotonin syndrome is the body’s reaction to an excess of serotonin. 

The syndrome is rare, but when it does occur, it usually begins within one day of taking too much of an SSRI. Serotonin syndrome is a medical emergency that causes high body temperatures, fever, shivering, muscle tightness, confusion, and potentially lethal seizures.

Reclaim Your Life With Sertraline Detox

Sertraline addiction is a condition that can cause major health, social and economic problems that should not be taken lightly. We Level Up California can provide you, or someone you love, the tools to recover from addiction with professional and safe Sertraline detox. Feel free to call us to speak with one of our counselors. We can inform you about this condition by giving you relevant information. Our specialists know what you are going through. Please know that each call is private and confidential.

Sources

[1] We Level Up Treatment Center – ‘Zoloft Withdrawal Treatment’

[2] Amsden GW, Georgian F. Orthostatic hypotension induced by sertraline withdrawal. Pharmacotherapy. 1996 Jul-Aug;16(4):684-6. PMID: 8840377. – National Library of Medicine (pubmed.ncbi.nlm.nih.gov)

[3] U.S. Food & Drug Administration (FDA) (https://www.fda.gov/)

[4] Amsden GW, Georgian F. Orthostatic hypotension induced by sertraline withdrawal. Pharmacotherapy. 1996 Jul-Aug;16(4):684-6. PMID: 8840377. – National Library of Medicine (pubmed.ncbi.nlm.nih.gov)

[5] We Level Up California – Zoloft, and Alcohol